环境化学与生态毒理学国家重点实验室

近期成果

1.     Shengxian Liang, Nuoya Yin, Francesco Faiola*. Human pluripotent stem cells as tools for predicting developmental neural toxicity of chemicals: strategies, applications and challenges. Stem Cells and Development. 2019, doi: 10.1089/scd.2019.0007.

2.     Shaojun Liang, Hui Zhou, Nuoya Yin, Yuanping Lu, Francesco Faiola*. Embryoid body-based RNA-seq analyses reveal a potential TBBPA multifaceted developmental toxicity. Journal of Hazardous Materials. 2019, 376, 223-232.

3.     Nuoya Yin, Xiaoxing Liang, Shengxian Liang, Shaojun Liang, Renjun Yang, Bowen Hu, Zhanwen Cheng, Shuyu Liu, Hengzhi Dong, Sijin Liu, Francesco Faiola*. Embryonic stem cell- and transcriptomics- based in vitro analyses reveal that bisphenols A, F and S have similar and very complex potential developmental toxicities. Ecotoxicology and Environmental Safety. 2019, 176, 330-338.

4.     Yang Zhang#, Nuoya Yin#, Shengxian Liang, Su Shen, Dandan Li, Francesco Faiola*. 5-fluorouracil-induced neurotoxicity in rat cerebellum granule cells involves oxidative stress and activation of caspase-3 pathway. International Journal of Clinical and Experimental Medicine. 2019, 12(3), 2334-2343.

5.     Shengxian Liang, Shaojun Liang, Nuoya Yin, Francesco Faiola*. Establishment of a human embryonic stem cell-based liver differentiation model for hepatotoxicity evaluations. Ecotoxicology Environmental Safety. 2019, 174, 353-362.

6.     Shuyu Liu, Renjun Yang, Nuoya Yin, Yuan-Liang Wang, Francesco Faiola*. Environmental and human relevant PFOS and PFOA doses alter human mesenchymal stem cell self-renewal, adipogenesis and osteogenesis. Ecotoxicology and Environmental Safety. 2019, 169, 564-572.

7.     Hengzhi Dong, Xinglei Yao, Shuyu Liu, Nuoya Yin, Francesco Faiola*. Non-cytotoxic nanomolar concentrations of bisphenol A induce human mesenchymal stem cell adipogenesis and osteogenesis. Ecotoxicology and Environmental Safety. 2018, 164, 448-454.

8.     Nuoya Yin#, Bowen Hu#, Renjun Yang, Shaojun Liang, Shengxian Liang, Francesco Faiola*. Assessment of the developmental neurotoxicity of silver nanoparticles and silver ions with mouse embryonic stem cells in vitro. Journal of Interdisciplinary Nanomedicine. 2018, 3(3), 133-145.

9.     Shuyu Liu, Nuoya Yin, Francesco Faiola*. PFOA and PFOS Disrupt the Generation of Human Pancreatic Progenitor Cells. Environmental Science & Technology Letters. 2018, 5(5), 237-242.

10.  Nuoya Yin#, Renjun Yang#, Shaojun Liang, Shengxian Liang, Bowen Hu, Ting Ruan, Francesco Faiola*. Evaluation of the early developmental neural toxicity of F-53B, as compared to PFOS, with an in vitro mouse stem cell differentiation model. Chemosphere. 2018, 204, 109-118.

11.  Nuoya Yin#, Shaojun Liang#, Shengxian Liang, Renjun Yang, Bowen Hu, Zhanfen Qin, Aifeng Liu, Francesco Faiola*. TBBPA and Its Alternatives Disturb the Early Stages of Neural Development by Interfering with the NOTCH and WNT Pathways. Environmental Science & Technology. 2018, 52 (9), 5459-5468.

12.  Nuoya Yin#, Shengxian Liang#, Shaojun Liang, Bowen Hu, Renjun Yang, Qunfang Zhou, Guibin Jiang, Francesco Faiola*. DEP and DBP induce cytotoxicity in mouse embryonic stem cells and abnormally enhance neural ectoderm development. Environmental Pollution. 2018, 236, 21-32.

13.  Francesco Faiola#,* Nuoya Yin#, Miguel Fidalgo, Xin Huang, Arven Saunders, Junjun Ding, Diana Guallar, Baoyen Dang, and Jianlong Wang*. NAC1 Regulates Somatic Cell Reprogramming by Controlling Zeb1 and E-cadherin Expression. Stem Cell Reports. 2017, 9 (3), 913-926.

14.  Shuyu Liu, Nuoya Yin, Francesco Faiola*. Prospects and Frontiers of Stem Cell Toxicology. Stem Cells & Development. 2017, 26 (21), 1528-1539.

15.  Xinglei Yao, Nuoya Yin, Francesco Faiola*. Stem cell toxicology: a powerful tool to assess pollution effects on human health. National Science Review. 2016, 3(4), 430-450.

16.  Nuoya Yin, Xinglei Yao, Zhanfen Qin, Yuan-Liang Wang, Francesco Faiola*. Assessment of Bisphenol A (BPA) neurotoxicity in vitro with mouse embryonic stem cells. Journal of Environmental Sciences. 2015, 36, 181-187.

17.  Francesco Faiola*, Nuoya Yin, Xinglei Yao, Guibin Jiang. The Rise of Stem Cell Toxicology. Environmental Science & Technology. 2015, 49 (10), 5847-5848.

18.  Nuoya Yin, Xinglei Yao, Qunfang Zhou, Francesco Faiola*, GuibinJiang. Vitamin E attenuates silver nanoparticle-induced effects on body weight and neurotoxicity in rats. Biochemical and Biophysical Research Communications. 2015, 458 (2), 405-410.

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