环境化学与生态毒理学国家重点实验室

近期成果

1.    Juan Ma, Peng He, Chuanfang Zhao, Q Ren, Z Dong, J Qiu, Y Jing, Sijin Liu*, Yuguo Du*, A Designed α-GalCer Analog Promotes Considerable Th1 Cytokine Response by Activating the CD1d-iNKT Axis and CD11b-Positive Monocytes/Macrophages, Advanced Science 2020, 2000609.

2.    Peng He, Chuanfang Zhao, Jiao Lu, Yang Zhang, Min Fang, and Yuguo Du*, Synthesis of 5-Thio-α-GalCer Analogues with Fluorinated Acyl Chain on Lipid Residue and Their Biological Evaluation. ACS Med Chem lett. 2019, 2, 221-225.

3.      Wen Q, Xie X, Zhao C, Ren Q, Zhang X, Wei D, Brice Emanuelli, Yuguo Du*. The brominated flame retardant PBDE 99 promotes adipogenesis via regulating mitotic clonal expansion and PPARgamma expression. Sci Total Environ 2019, 670, 67-77.

4.    Jialin Geng, Qidong Ren, Caizhu Chang, Xinni Xie, Jun Liu, Yuguo Du*. Synthesis and biological activities of petrosiols B and D, RSC Adv. 2019, 9, 10253-10263.

5.    Sun Xuefeng, Wei Dongbin*, Liu Wei, Geng Jialin, Liu Jun, Du Yuguo*, Formation of novel disinfection by-products chlorinated benzoquinone, phenyl benzoquinones and polycyclic aromatic hydrocarbons during chlorination treatment on UV filter 2,4-dihydroxy benzophenone in swimming pool water, J Hazard. Mater. 2019, 367, 725-733.

6.    Yi Liu, Peng He, Yang Zhang, Xiangyu Zhang, Jun Liu, Yuguo Du*, One-Pot Enantiomeric Synthesis of Thiazole-Containing Amino Acids: Total Synthesis of Venturamides A and B, J Org. Chem. 2018, 83, 3897-3905.

7.    Yong Wang, Miao Liu, Lei Liu, Jian-Hui Xia, Yu-Guo Du,* Jian-Song Sun*, The Structural Revision and Total Synthesis of Carambolaflavone A, J Org Chem. 2018, 83, 4111-4118.

8.    Junfei Qiao, Chuanfang Zhao, Jun Liu, Yuguo Du*, Design and synthesis of selenazole-substituted ritonavir analogs, Bioorg & Med Chem Lett. 2018, 28, 2379-2381.

9.    Junfei Qiao, Yi Liu, Yuguo Du*, Method to Build 2,4-Substituted Selenazole from β-Azido Diselenide and Carboxylic Acid: A Formal Synthesis of Selenazofurin, Tetrahedron, 2018, 74, 3061-3068.

10. Chengxiang Shang, Chao Cai, Cuixia Zhao, Yuguo Du*, Synthesis and anti-inflammatory activity of gold-nanoparticle bearing a dermatan sulfate disaccharide analog, Chin Chem Lett. 2018, 29, 81–83.

11. Yangguang Gao, Jun Liu, Junfei Qiao, Yuguo D, Stereoselective synthesis of (-)-synargentolide B, Tetrahedron Lett. 2018, 59, 291-294.

12. Jing Liu, Linlin Wang, Yuguo Du*, Sijin Liu*, An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress. Advanced Science 2017, 4, 1700089.

 

研究组近期发明专利:

 

1.       杜宇国、刘义、赵翠霞 ,检测金属离子Sn2+的探针分子设计、合成及应用,201810275392.0,

2.       杜宇国、耿佳琳、刘思金,Petrosiols A-E的合成方法及药用潜力,201711329092.82018.01.16初审)

3.       杜宇国、乔俊飞,具有抗HIV-1活性的Ritonavir硒唑衍生物及合成方法,201710721768.x2017.12.27初审)

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