简历：

彭汉勇，研究员/博士生导师，中国科学院生态环境研究中心环境化学与环境毒理全国重点实验室。研究内容聚焦前沿的环境与健康科学问题，发展生命体内分子鉴定、检测、成像和调控的先进手段，突破复杂环境和生物体系中关键分子毒性和功能研究的技术瓶颈，解析环境污染物健康效应的分子机制。学术论文发表期刊包括Nat. Commun., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Environ. Sci. Technol., Anal. Chem.等。  

教育与工作经历： 

2021. 01 -至今，中国科学院生态环境研究中心，环境化学与生态毒理学国家重点实验室，研究员 

2015. 01 -2020.12，阿尔伯塔大学临床医学和病理学院环境分析与毒理系，博士后 

2008. 09 - 2014.12，武汉大学化学与分子科学学院分析化学专业，博士 

2011. 10 - 2013. 09，阿尔伯塔大学临床医学和病理学院环境分析与毒理系，访问博士生 

2004. 09 – 2008. 07，武汉大学化学与分子科学学院化学基地班，学士

社会任职：

1. 担任Anal. Chem., J. Environ. Sci., E&H、环境化学、高等学校化学学报等期刊青年编委。

2. 担任中国分析测试协会质谱分会委员、原子光谱分会委员、智能医学检验分会副秘书长、环境分析分会委员等。

承担科研项目：

1. 主持国家高层次青年人才（海外）

2. 国家重点研发计划课题

3. 中国科学院先导专项B课题

4. 中国科学院稳定支持基础领域青年团队任务

5. 国家自然科学基金委员会面上基金等

获奖及荣誉：

2025年度 中国科学院大学“小米青年学者”

代表论著：

1.   Yuan, A. J.; Sha, R.; Xie, W. J.; Qu, G. B.; Zhang, H. Q.; Wang, H. L.; Le, X. C.; Jiang, G. B.; Peng, H. Y.* RNA-Activated CRISPR/Cas12a Nanorobots Operating in Living Cells. Journal of the American Chemical Society 2024, 146 (39), 26657–26666. (Supplementary Cover)

2.   Xie, W. J.; Hao, Q. J.; Ye, Z.; Sha, R.; Wen, B.; Wang, H. L.; Zhang, H. Q.; Jia, G. H.; Le, X. C.; Jiang, G. B.; Peng, H. Y.* Spherical Nucleic Acids-Directed Cryosynthesis of Manganese Nanoagents for Tumor Imaging and Therapy. Angewandte Chemie International Edition 2025, 64 (24), e202503004.

3.   Bu, L. Y.; Yuan, A. J.; Zhao, M. Q.; Pang, B.; Li, J.; Shang, Y. X.; Xie, W. J.; Peng, H. Y.* An Asymmetric Stem-Loop Translator Enhances Specificity of One-Pot Isothermal CRISPR/Cas12a Assay. Analytical Chemistry 2026, 98 (7), 5513–5522.

4.   Yuan, A. J.; Hao, H. F.; Sha, R.; Xiao, H.; Yang, F.; Pang, B.; Li, J. H.; Jin, M. H.; Xie, W. J.; Zhao, L. X.; Wang, Y. W.; Zhang, Y.; Li, J.; Peng, H. Y.* In Situ Imaging of Cellular Inflammatory Response to Antibiotic Exposure with a DNAzyme Nanorobot. Environmental Science & Technology 2024, 58 (46), 20619–20629.

5.   He, B. Y.; Wang, L. F.; Jin, X. Y.; Zhang, X.; Sha, R.; Liang, Y.; Wang, Y. W.; Xie, W. J.; Shi, J. B.; Peng, H. Y.* Porous Agarose Layered Magnetic Graphene Oxide Nanocomposite for Virus RNA Monitoring in Wastewater. Analytical Chemistry 2024, 96 (22), 9167–9176.

6.   Yuan, A. J.; Sun, T. R.; Chen, L. Y.; Zhang, D. P.; Xie, W. J.; Peng, H. Y.* CRISPR/Cas12a Corona Nanomachine for Detecting Circulating Tumor Nucleic Acids in Serum. Analytical Chemistry 2024, 96 (50), 20074–20081.

7.   Deng, Z. J.; Liao, W. J.; Bu, L. Y.; Li, J. H.; Li, J.; Wang, L. F.; Yuan, A. J.; Xie, W. J.; Wang, Y. W.; Peng, H. Y.* Advancements in CRISPR-Diagnostic Techniques for Rapid On-Site Monitoring of Environmental Virus. TrAC - Trends in Analytical Chemistry 2024, 181, 118046.

8.   Ye, Z.; Liao, W. J.; Deng, Z. J.; Wang, L. F.; Wen, B.; Zhang, D. P.; Wang, H. L.; Xie, W. J.; Peng, H. Y.* Fast-Track Synthesis of DNA-Functionalized Gold Nanoparticles for Biosensing Applications. TrAC - Trends in Analytical Chemistry 2024, 175, 117724.

9.   Yuan, A. J.; Xiao, H.; Yang, F.; Hao, H. F.; Wang, X. Y.; Li, J. H.; Jin, M. H.; Zhao, Q.; Sha, R.; Deng, Z. J.; Peng, H. Y.* DNA Walker for Signal Amplification in Living Cells. TrAC - Trends in Analytical Chemistry 2023, 158, 116870.

10. Feng, W.^#; Peng, H. Y.^#; Xu, J. Y.; Liu, Y. M.; Pabbaraju, K.; Tipples, G.; Joyce, M. A.; Saffran, H. A.; Tyrrell, D. L.; Babiuk, S.; Zhang, H. Q.; Le, X. C. Integrating Reverse Transcription Recombinase Polymerase Amplification with CRISPR Technology for the One-Tube Assay of RNA. Analytical Chemistry 2021, 93 (37), 12808–12816.

11. Wu, J. J.^#; Peng, H. Y.^#; Lu, X. F.; Lai, M. D.; Zhang, H. Q.; Le, X. C. Binding-Mediated Formation of Ribonucleoprotein Corona for Efficient Delivery and Control of CRISPR/Cas9. Angewandte Chemie International Edition 2021, 60 (20), 11104–11109.

12.  冯薇; 肖航; 袁爱姣; 邓兆佳; 王小燕; 彭汉勇*; 乐晓春. CRISPR单管等温扩增技术高灵敏检测核酸:以检测新型冠状病毒(SARS-CoV-2) RNA为例. 中国科学: 化学 2022, 52, 1685.

13. Peng, H. Y.; Le, C.; Wu, J. J.; Li, X.-F.; Zhang, H. Q.; Le, X. C. A Genome Editing Nanomachine Constructed with a Clustered Regularly Interspaced Short Palindromic Repeats System and Activated by Near-Infrared Illumination. ACS Nano 2020, 14, 2817–2826.

14. Peng, H. Y.; Newbigging, A.; Reid, M. S.; Uppal, J. S.; Xu, J.; Zhang, H.; Le, X. C. Signal Amplification in Living Cells: A Review of MicroRNA Detection and Imaging. Analytical Chemistry 2020, 92, 292–308.

15. Peng, H. Y.; Newbigging, A.; Wang, Z.; Tao, J.; Deng, W.; Le, X. C.; Zhang, H. Q. DNAzyme-Mediated Assays for Amplified Detection of Nucleic Acids and Proteins. Analytical Chemistry 2018, 90, 190–207.

16. Peng, H. Y.; Hu, B.; Liu, Q. Q.; Li, X.-F.; Zhang, H. Q.; Le, X. C. Methylated Phenylarsenical Metabolites Discovered in Chicken Liver. Angewandte Chemie International Edition 2017, 56, 6773–6777. (Cover)

17. Peng, H. Y.; Zhang, H.; Li, X.-F.; Le, X. C. A MicroRNA-Initiated DNAzyme Motor Operating in Living Cells. Nature Communications 2017, 8, 14378.

18. Feng, W.; Peng, H. Y.; Zhang, H. Q.; Weinfeld, M.; Le, X. C. A Sensitive Technique Unravels the Kinetics of Activation and Trans-Cleavage of CRISPR–Cas Systems. Angewandte Chemie International Edition 2024, 63 (22), e202404069.

19. Yang, Z. L.; Peng, H. Y.; Lu, X. F.; Liu, Q. Q.; Huang, R. F.; Hu, B.; Kachanoski, G.; Zuidhof, M. J.; Le, X. C. Arsenic Metabolites, Including N-Acetyl-4-Hydroxy-M-Arsanilic Acid, in Chicken Litter from a Roxarsone-Feeding Study Involving 1600 Chickens. Environmental Science & Technology 2016, 50, 6737–6743.

20. Liu, Q. Q.; Peng, H. Y.; Lu, X. F.; Zuidhof, M. J.; Li, X.-F.; Le, X. C. Arsenic Species in Chicken Breast: Temporal Variations of Metabolites, Elimination Kinetics, and Residual Concentrations. Environmental Health Perspectives 2016, 124, 1174–1181.

专著章节：

1. 彭汉勇*，严晓文*，景传勇*，刘晴晴，黄 科，孟晓光，王秋泉，赵方杰，乐晓春. 砷的环境行为、代谢机理、健康效应, 《原子光谱分析前沿》, 科学出版社, 2022.

2.   Hanyong Peng, Aijiao Yuan, Hang Xiao, Zi Ye, Lejun Liao, Shulin Zhao, and X. Chris Le. DNA Nanomotor for Bioimaging in Living Cells. DNA Nanotechnology for Cell Research: From Bioanalysis to Biomedicine [M]. John Wiley & Sons, 2024.