简历：

彭汉勇博士的研究内容涵盖分析化学、生物化学、环境毒理等多学科，聚焦前沿的环境与健康科学问题，发展分子鉴定、成像和调控的先进手段，突破复杂环境和生物体系中关键分子毒性和功能研究的技术瓶颈，并通过细胞和动物实验深入地研究环境污染物健康效应的分子机制。学术论文发表期刊包括Nat. Commun., Angew. Chem. Int. Ed., ACS nano, Environ. Health Persp., Anal. Chem., Environ. Sci. Technol. J. Anal. Atom. Spectrom., J. Chromatogr. A, Talanta等，并申请了两项美国授权专利。 

教育与工作经历：

2021. 01 -至今，中国科学院生态环境研究中心，环境化学与生态毒理学国家重点实验室，研究员
2015. 01 -2020.12，阿尔伯塔大学临床医学和病理学院环境分析与毒理系，博士后
2008. 09 - 2014.12，武汉大学化学与分子科学学院分析化学专业，博士
2011. 10 - 2013. 09，阿尔伯塔大学临床医学和病理学院环境分析与毒理系，访问博士生
2004. 09 – 2008. 07，武汉大学化学与分子科学学院化学基地班，学士

社会任职： 

承担科研项目： 

获奖及荣誉： 

代表论著：

1. Peng, H. Y., Le, C., Wu, J. J., Li, X. -F., Zhang, H. Q., Le, X. C. A genome editing nanomachine constructed with a clustered regularly interspaced short palindromic repeats system and activated by near-Infrared illumination. ACS Nano 2020, 14, 2817–2826.
2. Wu, J. J.# , Peng, H. Y#. , Lu, X. F., Lai, M., Zhang, H. Q., Le, X. C. Binding-mediated formation of ribonucleoprotein corona for efficient delivery and control of CRISPR-Cas9. Angewandte Chemie International Edition 2020, doi.org/10.1002/anie.202014162. (Co-first authors)
3. Pang, B., Xu, J. Y., Liu, Y. M., Peng, H. Y., Feng, W., Cao, Y. R., Wu, J. J., Xiao, H. Y., Pabbaraju, K., Tipples, G., Joyce, M. A., Saffran, H. A., Tyrrell, D. L., Zhang, H. Q. and Le, X. C. Isothermal Amplification and Ambient Visualization in a Single Tube for the Detection of SARS-CoV-2 Using Loop-Mediated Amplification and CRISPR Technology, Analytical Chemistry 2020, 92, 16204–16212.
4. Feng, W.#, Newbigging, A. M.#, Le, C.#, Pang, B.#, Peng, H. Y.#, Cao, Y. Wu, J. J., Abbas, G., Song, J., Wang, D. -B. Cui, M., Tao, J., Tyrrell, D. L., Zhang, X. -E., Zhang, H. Q., Le, X. C. Molecular diagnosis of COVID-19: Challenges and research needs. Analytical Chemistry 2020, 92, 10196–10209. (Co-first authors, Cover feature)
5. Peng, H. Y., Newbigging, A., Reid, M. S., Uppal, J. S., Xu, J., Zhang, H., Le, X. C. Signal amplification in living cells: A review of microRNA detection and imaging. Analytical Chemistry 2020, 92, 292-308.
6. Huang, K., Peng, H. Y., Gao, F., Liu, Q. Q., Lu, X. -F., Shen, Q. R., Le, X. C., Zhao, F. J. Biotransformation of arsenic-containing Roxarsone by an aerobic soil bacterium Enterobacter sp. CZ-1. Environmental Pollution 2019, 247, 482-487.
7. Peng, H. Y., Newbigging, A., Wang, Z., Tao, J., Deng, W., Le, X. C., Zhang, H. Q. DNAzyme-mediated assays for amplified detection of nucleic acids and proteins. Analytical Chemistry 2018, 90, 190-207.
8. Peng, H. Y., Hu, B., Liu, Q. Q., Li, X. -F., Zhang, H. Q., Le, X. C. Methylated phenylarsenical metabolites discovered in chicken liver. Angewandte Chemie International Edition 2017, 56, 6773–6777. (Cover feature)
9. Peng, H. Y., Zhang, H., Li, X. -F., Le, X. C. A microRNA-initiated DNAzyme motor operating in living cells. Nature Communications 2017, 8, 14378. (Highly cited)
10. Yang, Z. L., Peng, H. Y., Lu, X. F., Liu, Q. Q. Huang, R. F., Hu, B., Kachanoski, G., Zuidhof, M. J., Le, X. C. Arsenic metabolites, including N-acetyl-4-hydroxy-m-arsanilic acid, in chicken litter from a roxarsone-feeding study involving 1600 chickens. Environmental Science & Technology 2016, 50, 6737-6743.
11. Liu, Q. Q., Peng, H. Y., Lu, X. F., Zuidhof, M. J., Li, X. -F., Le, X. C. Arsenic species in chicken breast: temporal variations of metabolites, elimination kinetics, and residual Concentrations. Environmental Health Perspectives 2016, 124, 1174-1181.
12. Peng, H. Y., Zhang, N., He, M., Chen, B. B., Hu, B. Multi-wall carbon nanotubes chemically modified silica microcolumn preconcentration/separation combined with inductively coupled plasma optical emission spectrometry for the determination of trace elements in environmental waters. International Journal of Environmental Analytical Chemistry 2016, 96, 212-224.
13. Yan, X. W., Li, J. H., Liu, Q. Q., Peng, H. Y. Popowich, A., Wang, Z. X., Li, X. -F., Le, X. C. p-Azidophenylarsenoxide: A novel arsenical “bait” for the in-situ capture and identification of cellular arsenic-binding proteins. Angewandte Chemie-International Edition 2016, 55, 14051-14057.
14. Zhang, H., Zuehlke, A., Peng, H. Y., Lai, M., Li, X. -F., Le, X. C. Binding-induced DNA nanomachines triggered by proteins and nucleic acids. Angewandte Chemie International Edition 2015, 54, 14326-14330.
15.Peng, H. Y., Reid, M. S., Le, X. C. Consumption of rice and fish in an electronic waste recycling area contributes significantly to tot al daily intake of mercury. Journal of Environmental Sciences 2015, 38, 83-86.
16. Peng, H. Y., Zhang, N., He, M., Chen, B. B., Hu, B. Simultaneous speciation analysis of inorganic arsenic, chromium and selenium in environmental waters by 3-(2-aminoethylamino) propyltrimethoxysilane modified multi-wall carbon nanotubes packed microcolumn solid phase extraction and ICP-MS. Talanta 2015, 131, 266–272. (Highly cited)
17. Peng, H. Y., Hu, B., Liu, Q. Q., Yang, Z. L., Lu, X., Huang, R. F., Li, X. -F., Le X. C. Liquid chromatography combined with atomic and molecular mass spectrometry for speciation of arsenic in chicken liver. Journal of Chromatography A 2014, 1370, 40–49.
18. Peng, H. Y., Jiao, Y., Xiao, X., Chen, B. B., He, M., Liu, Z. R., Zhang, X., Hu, B. Magnetic quantitative analysis for multiplex glycoprotein with polymer-based elemental tags. Journal of Analytical Atomic Spectrometry 2014, 29, 1112-1119.
19. Peng, H. Y., Chen, B. B., He, M., Zhang, Y., Hu, B. Magnetic quantitative immunoanalysis of carcinoembryonic antigen by ICP-MS with mercury labels. Journal of Analytical Atomic Spectrometry 2011, 26, 1217-1223.
20. Chen, B. B.#, Peng, H. Y.#, Zheng, F., Hu, B., He, M., Zhao, W., Pang, D. W. Immunoaffinity monolithic capillary microextraction coupled with ICP-MS for immunoassay with quantum dot labels. Journal of Analytical Atomic Spectrometry 2010, 25, 1674-1681. (Co-first authors, Cover feature)
21. Liu, Q. Q., Peng, H. Y. Popowich, A., Tao, J., Uppal, J. S., Yan, X., Beo, D., Le, X. C. Speciation of arsenic–a review of phenylarsenicals and related arsenic metabolites. TrAC Trends in Analytical Chemistry 2018, 104, 171-182.
22. Chen, J., Zuehlke, A., Deng, B., Peng, H. Y., Hou, X., Zhang, H. A target-triggered DNAzyme motor enabling homogeneous, amplified detection of proteins. Analytical Chemistry 2017, 89, 12888-12895.
23. Moe, B., Peng, H.Y., Lu, X. F., Chen, B.W., Chen, L.W.L., Gabos, S., Li, X. -F., Le, X. C. Comparative cytotoxicity of fourteen trivalent and pentavalent arsenic species determined using real-time cell sensing. Journal of Environmental Sciences 2016, 49, 113-124.
24. Liu, Q.Q., Peng, H. Y., Lu X., Le, X. C. Enzyme-assisted extraction and liquid chromatography mass spectrometry for the determination of arsenic species in chicken meat. Analytica Chimica Acta 2015, 888, 1-9. (Cover feature)

专利：

1. Le, X. C., Zhang, H. Q., Peng, H. Y., Li, X.-F. A microRNA-initiated DNAzyme motor operating in living cells. United States. US 62/422,476. 2016/11/15.

2. Peng, H. Y., Zhang, H. Q., Li, X.-F., Le, X. C. Near-infrared photothermally activated CRISPR/Cas9 genome editing machine. United States. US 62/899,927. 2019/07/25