环境化学与生态毒理学国家重点实验室

胡立刚

发布时间：2019-06-06 | 【打印】【关闭】

姓名：胡立刚 [博士生导师]性别：男职称：研究员电话：010-62849129E-mail：lghu@rcees.ac.cn组别：金属污染物环境健康效应研究组研究方向：金属环境健康及环境地球化学循环机制研究招生专业：环境化学、环境健康、分析化学

简历：

　　教育经历

　　2001/09-2006/07，中国科学院生态环境研究中心环境化学与生态毒理国家重点实验室环境科学，博士导师：江桂斌院士

　　1993/09-1997/07，北京科技大学，工业分析，学士

　　工作经历

　　2016/06-至今，中国科学院生态环境研究中心，环境化学与生态毒理学国家重点实验室，研究员，博士生导师

　　2015/02-2016/05，中国科学院生态环境研究中心，环境化学与生态毒理学国家重点实验室，助理研究员

　　2010/01-2014/07，香港大学，博士后，合作导师：孙红哲

　　2006/11-2009/12，佛罗里达国际大学，博士后，合作导师：YC

　　社会任职：

　　1. 中国环境科学学会环境化学委员会委员

　　2. 中国仪器仪表协会分析仪器分会原子光谱专业委员会委员

　　3. 中国仪器仪表协会分析仪器分会离子色谱专业委员会委员

　　承担科研项目：

　　1. 国家自然科学基金委员会，重大项目，生命过程中外源污染物的暴露途径和归趋，2022-2026,431万，主持；

2. 国家“万人计划”领军人才项目，2024，主持

3. 国家自然科学基金重大研究计划重点支持项目（91743203），大气金属细颗粒物动物体内赋存研究方法及分布特征，2018/01-2021/12，295万，主持；

4. 海外高层次人才引进计划青年项目，环境与地球科学，2016-2019，300万，主持；

5. 国家重点研发计划，课题，污泥快速减量与资源化耦合利用技术，2020-2024,503万，主持；

6. 国家重点研发计划，子课题，合成生物系统在对持久性有毒污染物的感知与识别中的适用性及检测能力，2019-2024，132万，主持；

　　7. 国家自然科学基金面上项目（21677153），3D打印技术研制ICP-MS单细胞测定技术接口，2017/01-2020/12，68万，在研，主持；

　　8. 国家自然科学基金重点项目（21537004）子课题，复合纳米材料和高分辨质谱一体化结合的新型污染物复杂环境样品分析方法研究，2016/01-2020/12，344万，在研，参与。

　　获奖及荣誉：

　　1. 金属组学方法学及其应用，2021年中国分析测试协会科学技术奖（CAIA奖）特等奖

2. 中国分析测试协会2023BCEIA金奖（分析测试仪器零部件）

3. 2023 Dalton Horizon Prize of the royal society of chemistry

4. 2024年度中国仪器仪表学会科学仪器托举计划（CIS海豚计划）优秀研发团队项目

　　代表论著：

1. Yuanyuan Wang; Yiling Li; Qiying Nong; Guohuan Zhang; Nian Liu; Hua Guo; Qinghao He; Lihong Liu; Guangbo Qu; Bin He; Ligang Hu*; Guibin Jiang; Zinc-associated phospholipid metabolic alterations and their impacts on ALT levels in workers, Science of The Total Environment, 2024, 933: 173152

2. Hongzhe Dong; Yuchuan Wang; Tingting Zhi; Hua Guo; Yingying Guo; Lihong Liu; Yongguang Yin; Jianbo Shi; Bin He; Ligang Hu*; Guibin Jiang; Construction of protein-protein interaction network in sulfate-reducing bacteria: Unveiling of global response to Hg, Environmental Pollution, 2024, 351：124048

3. Jun Gao; Bin He; Baowei Chen; Yongguang Yin; Jianbo Shi; Minghui Zheng; Ligang Hu*; Guibin Jiang; Can Mercury Influence Carbon Dioxide Levels? Implications for the Implementation of the Minamata Convention on Mercury, Environmental Science & Technology, 2024, 58 (14): 6077-6082

4. Yingqiu Liu; Bin He*; Lihong Liu; Ligang Hu*; Guibin Jiang; Fasten the analysis of metal-binding proteins with GE-ICP-MS via increasing the electrolyte concentration of the running buffer, Talanta, 2024, 266

5. Xudong Guo; Dingyi Wang; Bin He; Ligang Hu; Guibin Jiang; 3D Bioprinting of Cultured Meat: A Promising Avenue of Meat Production, Food and Bioprocess Technology, 2024, 17: 1659–1680

6. Yinyin Tang, Lihong Liu*, Qinfei Zhou, Dingyi Wang, Hua Guo, Nian Liu, Xueting Yan, Zhenhua Wang, Bin He, Ligang Hu*, Guibin Jiang, Rapid determination of toxic and essential metal binding proteins in biological samples by size exclusion chromatography-inductively coupled plasma tandem mass spectrometry, Journal of Chromatography B, 2024, 124235

7. Haibo Wang†; Ligang Hu†; Hongyan Li†; Yau-Tsz Lai; Xueying Wei; Xiaohan Xu; Zhenkun Cao; Huiming Cao; Qianya Wan; Yuen-Yan Chang; Aimin Xu; Qunfang Zhou; Guibin Jiang; Ming-Liang He; Hongzhe Sun*; Mitochondrial ATP synthase as a direct molecular target of chromium(III) to ameliorate hyperglycaemia stress, Nature Communications, 2023, 14: 1738.

8. Hongzhe Dong; Lihong Liu*; Qinfei Zhou; Yinyin Tang; Huiling Wang; Yongguang Yin; Jianbo Shi; Bin He; Yanbin Li; Ligang Hu*; Guibin Jiang; Transformation of Mercuric Ions to Mercury Nanoparticles in Diatom Chaetoceros curvisetus, Environmental Science & Technology, 2023, 57(48): 19772–19781.

9. Qiying Nong; Baowei Chen; Yongshun Huang; Yiling Li; Yuanyuan Wang; Lihong Liu; Bin He; Tiangang Luan; Ligang Hu*; Guibin Jiang; Identification of lead-binding proteins as carriers and potential molecular targets associated with systolic blood pressure, Chemosphere, 2023, 341: 140138.

10. Junpeng Zhang; Dingyi Wang; Yingying Li; Lihong Liu; Yong Liang; Bin He; Ligang Hu*; Guibin Jiang; Application of three-dimensional printing technology in environmental analysis: A review, Analytica Chimica Acta, 2023, 1281: 341742.

11. Lei Li; Anthony S. Wexler; Xue Li*; Ligang Hu*; Guibin Jiang; In Situ Characterization of Bioaerosols at the Single-Particle Level Using Single-Particle Mass Spectrometry: A Promising Tool for Defending Human Health against Bioaerosol Transmission, Analytical Chemistry, 2023, 95(29): 10839–10843.

12. Hua Guo; Yinyin Tang; Yu Li; Haozhong Tian; Tingting Zhang; Yingying Li; Lihong Liu; Bin He*; Ligang Hu*; Guibin Jiang; Endocytosis-Mediated Transport of Pb in Rat Blood Cells, Environmental Science & Technology, 2023, 57(23): 8514–8523.

13. Yuanyuan Wang; Xiaoting Jin; Min Li; Jie Gao; Xingchen Zhao; Juan Ma; Chunzhen Shi; Bin He; Ligang Hu*; Jianbo Shi; Guoliang Liu; Guangbo Qu*; Yuxin Zheng; and Guibin Jiang; PM2.5 Increases Systemic Inflammatory Cells and Associated Disease Risks by Inducing NRF2-Dependent Myeloid-Biased Hematopoiesis in Adult Male Mice, Environmental Science & Technology, 2023, 57(21): 7924–7937.

14. Nian Liu; Heng-Gui Chen; Yu Li; Guohuan Zhang; Jie Zhang; Guangbo Qu; Bin He; Tian-Qing Meng; Cheng-Liang Xiong; An Pan; Yongguang Yin; Yong Liang; Jianbo Shi; Yi-Xin Wang*; Ligang Hu*; and Guibin Jiang; Exogenous Metals Atlas in Spermatozoa at Single-Cell Resolution in Relation to Human Semen Quality, Environmental Science & Technology, 2023, 57(19): 7358–7369.

15. Dingyi Wang; Tingting Zhang; Xudong Guo; Dayi Ling; Ligang Hu*; Guibin Jiang; The potential of 3D printing in facilitating carbon neutrality, Journal of Environmental Sciences, 2023, 130: 85-91.

16. Nian Liu, Yu Li, Lihong Liu, Xiaolei Liu, Yongguang Yin, Guangbo Qu, Jianbo Shi, Maoyong Song, Bin He, Ligang Hu *, and Guibin Jiang. Administration of Silver Nasal Spray Leads to Nanoparticle Accumulation in Rat Brain Tissues. Environmental Science & Technology, 2022, 56, 1, 403–413

17. Dingyi Wang, Tingting Zhi, Lihong Liu, Li Yan, Wei Yan, Yinyin Tang, Bin He, Ligang Hu*, Chuanyong Jing, Guibin Jiang, 3D printing of TiO2 nano particles containing macrostructures for As(III) removal in water, Science of The Total Environment, 2022, 815, 152754

18. Ligang Hu, Jie Gao, Linlin Yao, Li Zeng, Qian Liu, Qunfang Zhou, Haiyan Zhang, Dawei Lu, Jianjie Fu, Qian S. Liu, Min Li, Xingchen Zhao, Xingwang Hou, Jianbo Shi, Lihong Liu, Yingying Guo, Yawei Wang, Guang-Guo Ying, Yong Cai, Maosheng Yao, Zongwei Cai, Yongning Wu, Guangbo Qu*, and Guibin Jiang. Evidence of Foodborne Transmission of the Coronavirus (COVID-19) through the Animal Products Food Supply Chain. Environmental Science & Technology, 2021, 55, 5, 2713–2716.

19. Liu, Nian; Zhang, Huazhou; Tao, Chen; Zhang, Aiqian; Yin, Yongguang; Song, Maoyong; Qu, Guangbo; Shi, Jianbo; He, Bin; Hu, Ligang; Jiang, Guibin; Unified Probability Distribution and Dynamics of Lead Contents in Human Erythrocytes Revealed by Single-Cell Analysis, Environmental Science & Technology, 2021, 55(6), 3819-3826

20. Lihong Liu, Yongguang Yin, Ligang Hu*, Bin He, Jianbo Shi and Guibin Jiang. Revisiting the forms of trace elements in biogeochemical cycling: analytical needs and challenges. TRAC-Trends in Analytical Chemistry, 2020, 129, 115953

21. Baowei Chen, Ligang Hu*, Bin He, Tiangang Luan, Guibin Jiang, Environmetallomics: Systematically investigating metals in environmentally relevant media. TRAC-Trends in Analytical Chemistry, 2020, 126, 115875

22. Yuzhen Sun, Nian Liu, Yuanyuan Wang, Yongguang Yin, Guangbo Qu, Jianbo Shi, Maoyong Song, Ligang Hu*, Bin He, Guibin Jiang; Monitoring AuNP Dynamics in the Blood of a Single Mouse Using Single Particle Inductively Coupled Plasma Mass Spectrometry with an Ultralow-Volume High-Eﬃciency Introduction System, Analytical Chemistry, 2020, 92(22), 14872-14877

23. Dingyi Wang, Junpeng Zhang, Qian Liu, Ligang Hu, and Guibin Jiang, 3D Printing Challenges in Enabling Rapid Response to Public Health Emergencies, The Innovation, 2020, 1(3), 1-2

24. Dingyi Wang, Bin He, Xueting Yan, Qiying Nong, Ligang Hu, Guibin Jiang, 3D printed gel electrophoresis device coupling with ICP-MS for online separation and detection of metalloproteins, Talanta, 2019, 197, 145-150

25. Chengbin Zheng, Ligang Hu, Xiandeng Hou, Bin He*, and Guibin Jiang, Headspace Solid-Phase Microextraction Coupled to Miniaturized Microplasma Optical Emission Spectrometry for Detection of Mercury and Lead, Analytical Chemistry, 2018, 90(6), 3683-3691

26. Dingyi Wang, Xiu Huang, Jie Li, Bin He, Qian Liu, Ligang Hu and Guibin Jiang, 3D printing of graphene-doped target for ‘matrix-free’ laser desorption/ionization mass spectrometry, Chemical communications, 2018, 54(22), 2723-2726

27. Yiling Li, Bin He, Qiying Nong, Guangbo Qu, Lihong Liu, Jianbo Shi, Ligang Hu * and Guibin Jiang. Characterization of mercury-binding proteins in rat blood plasma, Chemical Communications, 2018, 54, 7439-7442.

28. Ligang Hu and Guibin Jiang*. 3D Printing Techniques in Environmental Science and Engineering Will Bring New Innovation, Environmental Science & Technology, 2017, 51(7): 3597-3599

29. Yau-Tsz Lai^#, Yuen-Yan Chang^#, Ligang Hu^#, Ya Yang, Ailun Chao, Zhi-Yan Du, Julian A Tanner, Mee-Len Chye, Chengmin Qian, Kwan-Ming Ng, Hongyan Li, Hongzhe Sun*. Rapid labeling of intracellular His-tagged proteins in living cells, Proceedings of the National Academy of Sciences of the United States of America, 2015, 112(10): 2948-2953

30. Lihong Liu, Bin He, Qian Liu *, Zhaojun Yun, Xueting Yan, Yanmin Long and Guibin Jiang*. Identification and accurate size characterization of nanoparticles in complex media. Angewandte Chemie International Edition, 2014, 53, 14476-14479 (VIP paper)

31. Ligang Hu, Tianfan Cheng, Bin He, Lu Li, Yuchuan Wang, Yau-Tsz Lai, Guibin Jiang, Hongzhe Sun*. Identification of Metal-Associated Proteins in Cells by Using Continuous-Flow Gel Electrophoresis and Inductively Coupled Plasma Mass Spectrometry. Angewandte Chemie-International Edition, 2013, 52(18): 4916-4920

32. 污泥在土壤资源化利用中的风险检测方法, 2021, 发明专利，授权专利号: ZL202110174167.X

33. 铅结合蛋白基因、包含其的蛋白及其应用, 2020, 发明专利, 授权专利号: HK18114871.5

34. 用于蛋白分离的水平柱状凝胶电泳装置, 2020, 发明专利, 授权专利号: ZL201611101473.6

35. 用于蛋白分离的电泳槽及采用其的柱状凝胶电泳装置, 2019, 发明专利, 授权专利号: ZL201611101526.4

36. 用于蛋白分离的洗脱装置及采用其的柱状凝胶电泳装置, 2019, 发明专利, 授权专利号: ZL201611101565.4

37. 基质辅助激光解吸-串联飞行时间质谱仪靶板, 2018, 发明专利, 授权专利号: ZL201710371403.0