环境化学与生态毒理学国家重点实验室

近期成果

1、发表论文

1)     Nian Liu, Yu Li, Lihong Liu, Xiaolei Liu, Yongguang Yin, Guangbo Qu, Jianbo Shi, Maoyong Song, Bin He, Ligang Hu*, and Guibin Jiang. Administration of Silver Nasal Spray Leads to Nanoparticle Accumulation in Rat Brain Tissues. Environmental Science & Technology, 2022, 56, 1, 403–413

2)   Dingyi Wang, Tingting Zhi, Lihong Liu, Li Yan, Wei Yan, Yinyin Tang, Bin He, Ligang Hu*, Chuanyong Jing, Guibin Jiang, 3D printing of TiO2 nano particles containing macrostructures for As(III) removal in water, Science of The Total Environment, 2022, 815, 152754

3)   Haozhong Tian, Bin He, Yongguang Yin, Lihong Liu, Jianbo Shi, Ligang Hu* and Guibin Jiang, Chemical Nature of Metals and Metal-Based Materials in Inactivation of Viruses, Nanomaterials, 2022, 12(14), 2345

4)   Yinyin Tang, Lihong Liu*, Qiying Nong, Hua Guo, Qinfei Zhou, Dingyi Wanga, Yongguang Yin, Jianbo Shi, Bin He, Ligang Hu*, Guibin Jiang, Sensitive determination of metalloprotein in salt-rich matrices by size exclusion chromatography coupled with inductively coupled plasma-mass spectrometry, Journal of Chromatography A, 2022, 1677, 463303

5)    Nian Liu, Guangbo Qu, Ruoxi Wen, Xiaolei Liu, Yuanyuan Wang, Jie Gao, Yongguang Yin, Jianbo Shi, Qunfang Zhou, Bin He, Ligang Hu, Guibin Jiang,  Occurrence of silver-containing particles in rat brains upon intranasal exposure of silver nanoparticles, Metallomics, DOI:10.1093/mtomcs/mfab077

6)   Qinghao He†, Jing Lu†, Nian Liu†, Wenqing Lu, Yu Li, Chao Shang*, Xiao Li*, Ligang Hu* and Guibin Jiang, Antiviral Properties of Silver Nanoparticles against SARS-CoV-2: Effects of Surface Coating and Particle Size, Nanomaterials, 2022, 12(6), 990

7)   Ligang Hu, Jie Gao, Linlin Yao, Li Zeng, Qian Liu, Qunfang Zhou, Haiyan Zhang, Dawei Lu, Jianjie Fu, Qian S. Liu, Min Li, Xingchen Zhao, Xingwang Hou, Jianbo Shi, Lihong Liu, Yingying Guo, Yawei Wang, Guang-Guo Ying, Yong Cai, Maosheng Yao, Zongwei Cai, Yongning Wu, Guangbo Qu*, and Guibin Jiang. Evidence of Foodborne Transmission of the Coronavirus (COVID-19) through the Animal Products Food Supply Chain. Environmental Science & Technology, 2021, 55, 5, 2713–2716.

8)   Liu, Nian; Zhang, Huazhou; Tao, Chen; Zhang, Aiqian; Yin, Yongguang; Song, Maoyong; Qu, Guangbo; Shi, Jianbo; He, Bin; Hu, Ligang; Jiang, Guibin; Unified Probability Distribution and Dynamics of Lead Contents in Human Erythrocytes Revealed by Single-Cell Analysis, Environmental Science & Technology, 2021, 55(6), 3819-3826

9)   Gao, Jie; Wang, Shunhao; Tang, Gang; Wang, Ziniu; Ma, Junjie; Wang, Yuanyuan; Liu, Yaquan; Guo, Hao; Li, Junya; Lv, Meilin; Li, Danyang; Hu, Ligang; Shi, Jianbo; He, Bin; Qu, Guangbo; Jiang, Guibin; Altered immune cells in the liver and spleen of mice as a typical immune response to graphene oxide exposure, Materials & Design, 2021,206,109802

10) Lihong Liu, Yongguang Yin, Ligang Hu*, Bin He, Jianbo Shi and Guibin Jiang. Revisiting the forms of trace elements in biogeochemical cycling: analytical needs and challenges. TRAC-Trends in Analytical Chemistry, 2020, 129, 115953

11) Baowei Chen, Ligang Hu*, Bin He, Tiangang Luan, Guibin Jiang, Environmetallomics: Systematically investigating metals in environmentally relevant media. TRAC-Trends in Analytical Chemistry, 2020, 126, 115875

12) Yuzhen Sun, Nian Liu, Yuanyuan Wang, Yongguang Yin, Guangbo Qu, Jianbo Shi, Maoyong Song, Ligang Hu*, Bin He,   Guibin Jiang; Monitoring AuNP Dynamics in the Blood of a Single Mouse Using Single Particle Inductively Coupled Plasma Mass Spectrometry with an Ultralow-Volume High-Efficiency Introduction System, Analytical Chemistry,  2020, 92(22), 14872-14877

13) Yiling Li, Bin He, Runzeng Liu, Guangbo Qu, Yongguang Yin, Jianbo Shi, Ligang Hu, Guibin Jiang; Cadmium-binding proteins in human blood plasma, Ecotoxicology and Environmental Safety,  2020, 188(2), 109896-109902

14) Dingyi Wang, Junpeng Zhang, Qian Liu, Ligang Hu, and Guibin Jiang, 3D Printing Challenges in Enabling Rapid Response to Public Health Emergencies, The Innovation,  2020, 1(3), 1-2

15) Dingyi Wang, Bin He, Xueting Yan, Qiying Nong, Ligang Hu, Guibin Jiang, 3D printed gel electrophoresis device coupling with ICP-MS for online separation and detection of metalloproteins, Talanta, 2019, 197, 145-150

16) Yiling Li, Mengni Zhang, Chengbin Zheng, Ligang Hu, Bin He, Guibin Jiang, Analysis of silver-associated proteins in pathogen via combination of native SDS-PAGE, fluorescent staining, and inductively coupled plasma mass spectrometry, Journal of Chromatography A, 2019, 1607, 460393

17) Dingyi Wang, Zhihua Ren, Bin He, Qunfang Zhou, Ligang Hu, Guibin Jiang, A case report of conjoined twins in medaka fish, Molecular Reproduction and Development, 2019, 86(9), 1083-1085

18) Cao Dandan, Yin Yongguang, He, Bin, Speciation of organomercury compounds by capillary electrophoresis with pre-column derivatization and on-line stacking, Chinese Chemical Letters, 2019, 30(3), 650-652

19) Lihong Liu, Yu Zhang, Zhaojun Yun, Bin He*, Qinghua Zhang, Ligang Hu and Guibin Jiang. Speciation and bioaccessibility of arsenic in traditional Chinese medicines and assessment of its potential health risk. Science of the Total Environment, 2018, 619-620, 1088-1097.

20) Xueting Yan, Bin He*, Ligang Hu*, Jiejun Gao, Shuai Chen, Guibin Jiang, Insight into the endocrine disrupting effect and cell response to butyltin compounds in H295R cell: Evaluated with proteomics and bioinformatics analysis, Science of The Total Environment, 2018, 628-629, 1489-1496

21) Chengbin Zheng, Ligang Hu, Xiandeng Hou, Bin He*, and Guibin Jiang, Headspace Solid-Phase Microextraction Coupled to Miniaturized Microplasma Optical Emission Spectrometry for Detection of Mercury and Lead, Analytical Chemistry, 2018, 90(6), 3683-3691

22) Dingyi Wang, Xiu Huang, Jie Li, Bin He, Qian Liu, Ligang Hu and Guibin Jiang, 3D printing of graphene-doped target for ‘matrix-free’ laser desorption/ionization mass spectrometry, Chemical communications, 2018, 54(22), 2723-2726

23) Yiling Li, Bin He, Qiying Nong, Guangbo Qu, Lihong Liu, Jianbo Shi, Ligang Hu * and Guibin Jiang. Characterization of mercury-binding proteins in rat blood plasma, Chemical Communications, 2018, 54, 7439-7442.

24) Yiling Li, Bin He, Jiejun Gao, Qian S. Liu, Runzeng Liu, Guangbo Qu, Jianbo Shi,Ligang Hu, Guibin Jiang, Methylmercury exposure alters RNA splicing in human neuroblastoma SK-N-SH cells: Implications from proteomic and post-transcriptional responses, Environmental Pollution, 2018, 238, 213-221

25) Xueting Yan, Bin He⁎, Lihong Liu, Guangbo Qu, Jianbo Shi, Chunyang Liao, Ligang Hu⁎, Guibin Jiang. Organotin Exposure Stimulates Steroidogenesis in H295R Cell via cAMP Pathway. Ecotoxicology and Environmental Safety, 2018, 156, 148-153.

26) Yiling Li, Bin He, Ligang Hu, Xiu Huang, Zhaojun Yun, Runzeng Liu, Qunfang Zhoua, Guibin Jiang, Characterization of mercury-binding proteins in human neuroblastoma SK-N-SH cells with immobilized metal affinity chromatography, Talanta, 2018, 178, 811-817

27) Xueting Yan, Bin He*, Dingyi Wang, Ligang Hu*, Lihong Liu, Chunyang Liao, Guibin Jiang. Two-dimensional (Weak Anion Exchange Chromatography-Gel Electrophoresis) Separations Coupling to Inductively Coupled Plasma Mass Spectrometry Strategy for Analysis of Metalloproteins. Talanta, 2018, 184, 404-410

28) Xueting Yan, Bin He*, Lihong Liu, Guangbo Qu, Jianbo Shi, Ligang Hu*, Guibin Jiang. Antibacterial Mechanism of Silver Nanoparticles in Pseudomonas aeruginosa: Proteomics approach. Metallomics, 2018, 10, 557-564

29) Ligang Hu and Guibin Jiang*. 3D Printing Techniques in Environmental Science and Engineering Will Bring New Innovation, Environmental Science & Technology, 2017, 51(7): 3597-3599

30) Yau-Tsz Lai#, Yuen-Yan Chang#, Ligang Hu#, Ya Yang, Ailun Chao, Zhi-Yan Du, Julian A Tanner, Mee-Len Chye, Chengmin Qian, Kwan-Ming Ng, Hongyan Li, Hongzhe Sun*. Rapid labeling of intracellular His-tagged proteins in living cells, Proceedings of the National Academy of Sciences of the United States of America, 2015, 112(10): 2948-2953

31) Lihong Liu, Bin He, Qian Liu*, Zhaojun Yun, Xueting Yan, Yanmin Long and Guibin Jiang*. Identification and accurate size characterization of nanoparticles in complex media. Angewandte Chemie International Edition, 2014, 53, 14476-14479 (VIP paper)

32) Ligang Hu, Tianfan Cheng, Bin He, Lu Li, Yuchuan Wang, Yau-Tsz Lai, Guibin Jiang, Hongzhe Sun*. Identification of Metal-Associated Proteins in Cells by Using Continuous-Flow Gel Electrophoresis and Inductively Coupled Plasma Mass Spectrometry. Angewandte Chemie-International Edition, 2013, 52(18): 4916-4920

33) 刘念,王园园,胡新笑,何滨,曲广波,史建波,胡立刚,江桂斌, 单细胞分析技术在人类细胞图谱计划中的应用, 中国科学化学, 2018, 48(10), 1217-1225

34) 李莹莹,王丁一, 农骐郢,刘丽红,张蒙,梁勇,胡立刚*,何滨,江桂斌,3D打印便携式凝胶电泳装置用于蛋白质的快速检测,色谱20203811),1316-1322

 

2、申请及授权专利

(1) 污泥在土壤资源化利用中的风险检测方法, 2021, 发明专利,授权专利号: ZL202110174167.X

(2) 铅结合蛋白基因、包含其的蛋白及其应用, 2020, 发明专利, 授权专利号: HK18114871.5

(3) 用于蛋白分离的水平柱状凝胶电泳装置, 2020, 发明专利, 授权专利号: ZL201611101473.6

(4) 用于蛋白分离的电泳槽及采用其的柱状凝胶电泳装置, 2019, 发明专利, 授权专利号: ZL201611101526.4

(5) 用于蛋白分离的洗脱装置及采用其的柱状凝胶电泳装置, 2019, 发明专利, 授权专利号: ZL201611101565.4

(6) 基质辅助激光解吸-串联飞行时间质谱仪靶板, 2018, 发明专利, 授权专利号: ZL201710371403.0

(7) 雾化室、采用其的进样系统和ICP-MS, 2018,  发明专利, 授权专利号: ZL201610227306.X

(8) 用于单细胞分析的电感耦合等离子体质谱进样系统, 2020, 实用新型, 授权专利号: ZL202020409667.8

(9) 金属蛋白分析系统, 2020, 实用新型, 授权专利号: ZL202020409681.8

(10) 高通量微量自动进样系统, 2019, 实用新型, 授权专利号: ZL201821486969.4

(11) 雾化室, 2020, 外观设计专利,授权专利号: ZL202030108014.1

(12) 水平柱状凝胶电泳槽, 2020, 外观设计专利,授权专利号: ZL202030108015.6

(13) 面罩型呼吸采样器及呼吸测试面罩, 2021, 发明专利, 专利号: CN113188853A

(14) 血桥限位器, 2021, 发明专利,专利号: CN113081079A

(15) 呼气代谢测定系统, 2021, 发明专利, 专利号: CN113009125A

(16) 用于模式鱼类胚胎连续培养及观测的装置和方法, 2020, 发明专利,专利号: CN111849772A

(17)用于红细胞的单个细胞标记的试剂盒及其检测方法, 2020, 发明专利,专利号: CN111157433A

(18) 用于重金属污染物吸附的负载结构及其制备方法与应用, 2019, 发明专利,专利号: CN109603746A

(19) 大气中持久性有机污染物主动采样套筒, 2018, 发明专利,专利号: CN107843463A

(20) 用于蛋白分离的柱状凝胶管及采用其的柱状凝胶电泳装置, 2017, 发明专利,专利号: CN106769357A

 

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