环境化学与生态毒理学国家重点实验室

近期成果

1.       Yuan-Yuan Li, Jin-Bo Li, Yan-Ping Shen, Yi-Ming Xiong, Xing-Hong Li, Zhan-Fen Qin* 2021 Identification of estrogen receptor target genes involved in gonadal feminization caused by estrogen in Xenopus laevis. Aquatic Toxicology 232, 105760.

2.       Chen Zhao, Ji-Fang-Tong Li, Xing-Hong Li*, Meng-Qi Dong, Yuan-Yuan Li, Zhan-Fen Qin. Measurement of polychlorinated biphenyls with hand wipes and matched serum collected from Chinese E-waste dismantling workers: Exposure estimates and implications. Science of the Total Environment. 2021, 799: 14944.

3.       Yue Niu, Min Zhu, Meng-Qi Dong, Jin-Bo Li, Yuan-Yuan Li, Yi-Ming Xiong, Peng-Yan Liu, Zhan-Fen Qin*. Bisphenols disrupt thyroid hormone (TH) signaling in the brain and affect TH-dependent brain development in Xenopus laevis. Aquatic Toxicology. 2021, 237,105902.

4.       Jun-Fa Yin, Ji-Fang-Tong Li, Xing-Hong Li*, You-Lin Yang, Zhan-Fen Qin. Bioaccumulation and transfer characteristics of dechlorane plus in human adipose tissue and blood stream and the underlying mechanisms. Science of the Total Environment. 2020, 700: 134391.

5.       Min Zhu, Yuan-Yuan Li, Yue Niu, Jin-Bo Li, Zhan-Fen Qin*. Effects of bisphenol A and its alternative bisphenol F on Notch signaling and intestinal development: A novel signaling by which bisphenols disrupt vertebrate development. Environmental Pollution, 2020, 263 (Pt B): 114443.

6.       Man Cai, Yuan-Yuan Li, Min Zhu, Jin-Bo Li, Zhan-Fen Qin*. Evaluation of the effects of low concentrations of bisphenol AF on gonadal development using the Xenopus laevis model: A finding of testicular differentiation inhibition coupled with feminization. Environmental Pollution, 2020, 260: 113980.

7.       Jin-Bo Li, Yuan-Yuan Li, Yan-Ping Shen, Min Zhu, Xing-Hong Li, Zhan-Fen Qin*. 2,2',4,4'-tetrabromodipheny ether (BDE-47) disrupts gonadal development of the Africa clawed frog (Xenopus laevis). Aquatic Toxicology. 2020, 221: 105441.

8.       Yan-Ping Shen, Yuan-Yuan Li, Min Zhu, Jin-Bo Li, Zhan-Fen Qin*. Transcriptional changes caused by estrogenic endocrine disrupting chemicals in gonad-mesonephros complexes of genetic male Xenopus laevis: Multiple biomarkers for early detection of testis differentiation disruption. Science of the Total Environment. 2020, 726: 138522.

9.       Yuan-Yuan Li, Yan-Ping Shen, Jin-Bo Li, Man Cai, Zhan-Fen Qin*. Transcriptomic analysis identifies early cellular and molecular events by which estrogen disrupts testis differentiation and causes feminization in Xenopus laevis. Aquatic Toxicology. 2020, 226: 105557.

10.     Hai-Yan Pan, Ji-Fang-Tong Li, Xing-Hong Li*, You-Lin Yang, Zhan-Fen Qin, Jin-Bo Li, Yuan-Yuan Li. Transfer of dechlorane plus between human breast milk and adipose tissue and comparison with legacy lipophilic compounds. Environmental Pollution. 2020, 265: 115096.

11.     Min Zhu, Xiao-Ying Chen, Yuan-Yuan Li, Nuo-Ya Yin, Francesco Faiola, Zhan-Fen Qin*, Wu-Ji Wei*. Bisphenol F disrupts thyroid hormone signaling and postembryonic development in Xenopus laevis. Environmental Science & Technology, 2018, 52(3): 1602-1611.

12.     Yuan-Yuan Li, Tan Meng, Kun Gao, Zhan-Fen Qin*. Gonadal differentiation and its sensitivity to androgens during development of Pelophylax nigromaculatus. Aquatic Toxicology, 2018, 202: 188-195.

13.     Yin-Feng Zhang, Xiao-Min Re, Yuan-Yuan Li, Xiao-Fang Yao, Chuan-Hai Li,Zhan-Fen Qin*, Liang-Hong Guo. Bisphenol A alternatives bisphenol S and bisphenol F interfere with thyroid hormone signaling pathway in vitro and in vivo. Environmental Pollution, 2018, 237: 1072-1079.

14.     Peng-Yan Liu, Tan Meng, Yuan-Yuan Li, Man Cai, Xing-Hong Li, Juan Chen, Zhanfen Qin*. Tetrabromoethylcyclohexane affects gonadal differentiation and development in the frog Pelophylax nigromaculatus. Aquatic Toxicology, 2017, 192: 40-47.

15.     Mei-Yun Zheng, Xing-Hong Li*, Yun Zhang, You-Lin Yang, Wen-Yue Wang, Yuan Tian., Partitioning of polybrominated biphenyl eEthers from mother to fetus and potential related health implications. Chemosphere, 2017, 170, 207-215.

16.     Ping-Fan Wu, Lian-Lian Yu, Long Li, Yun Zhang, Xing-Hong Li*. Maternal transfer of dechloranes and their distribution among tissues in contaminated ducks. Chemosphere, 2016, 150: 514-519.

17.     Yuan-Yuan Li, Juan Chen, Zhan-Fen Qin*. Determining the optimal developmental stages of Xenopus laevis forinitiating exposures to chemicals for sensitively detecting their feminizing effects on gonadal differentiation. Aquatic Toxicology, 2016, 179: 134–142.

18.     Ya-Xian Zhao, Yuan-Yuan Li, Xiao-Fei Qin, Qin-Qin Lou, Zhan-Fen Qin*. Accumulation of polybrominated diphenyl ethers in the brain compared with the levels in other tissues among different vertebrates from an e-waste recycling site. Environmental Pollution, 2016, 218: 1334-1341.

 

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