简历：

　　教育经历/br> 2007/09-2013/06，中国科学院生态环境研究中心 环境化学与生态毒理国家重点实验室 环境科学，博士 导师：朱本占研究员/br> 2003/09-2007/06，中国石油大学（北京） 资源与信息学院 获学士学位/br> 工作经历/br> 2015/08-至今，中国科学院生态环境研究中心，环境化学与生态毒理学国家重点实验室，助理研究员/br> 2013/07-2015/08，中国科学院生态环境研究中心，环境化学与生态毒理学国家重点实验室，博士后

 

　　承担科研项目：

　　1. 国家自然科学基金面上项目，21777180，多环芳胺致癌的新型光致活性自由基的生成及DNA损伤机理研究， 2018/01-2021/12，64万元，在研，主持。

　　2. 国家自然科学基金青年基金项目，21407163，四氯邻苯二酚与叠氮钠协同毒性分子机理，2014/01-2017/12，26万元，结题，主持。

　　

　　代表论著：

　

1.     Xu D,Huang C H*, Xie L N, Shao B, Mao L, Shao J, Kalyanaraman B, Zhu B Z*, Mechanism of unprecedented hydroxyl radical production and site-specific oxidative DNA damage by photoactivation of the classic arylhydroxamic acid carcinogens,Carcinogenesis, 2019:

2.     Huang C H, Ren F R, Shan G Q, Qin H, Mao L, Zhu B Z*, Molecular Mechanism of Metal-Independent Decomposition of Organic Hydroperoxides by Halogenated Quinoid Carcinogens and the Potential Biological Implications, Chem Res Toxicol, 2015,28(5): 831-837

3.     Huang C H, Shan G Q, Mao L, Kalyanaraman B, Qin H, Ren F R, Zhu B Z*, The first purification and unequivocal characterization of the radical form of the carbon-centered quinone ketoxy radical adduct, Chem Commun, 2013,49(57): 6436-6438

4.     Zhu B Z*, Chao X J,Huang C H, Li Y, Delivering the cell-impermeable DNA ‘lightswitching’Ru(II) complexes preferentially into live cell nucleus via an unprecedented ion-pairing method,Chem Sci, 2016,(7): 4016-4023

5.     Zhu B Z*, Mao L,Huang C H, Qin H, Fan R M, Kalyanaraman B, Zhu J G, Unprecedented hydroxyl radical-dependent two-step chemiluminescence production by polyhalogenated quinoid carcinogens and H₂O₂,Proc Natl Acad Sci USA, 2012,109(40): 16046-16051

6.     Zhu B Z*, Shan G Q,Huang C H, Kalyanaraman B, Mao L, Du Y G, Metal-independent decomposition of hydroperoxides by halogenated quinones: Detection and identification of a quinone ketoxy radical,Proc Natl Acad Sci USA, 2009,106(28): 11466-11471

7.     Li F,Huang C H, Xie L N, Qu N, Shao J, Shao B, Zhu B Z*, An Exceptionally Facile Two-Step Structural Isomerization and Detoxication via a Water-Assisted Double Lossen Rearrangement,Sci Rep, 2016,6:

8.     Li Y,Huang C H, Liu Y X, Mao L, Zhu B Z*, Detoxifying Polyhalogenated Catechols through a Copper-Chelating Agent by Forming Stable and Redox-Inactive Hydrogen-Bonded Complexes with an Unusual Perpendicular Structure,Chemistry-a European Journal, 2014,20(40): 13028-13033

9.     Shao J,Huang C H, Kalyanaraman B, Zhu B Z*, Potent methyl oxidation of 5-methyl-2'-deoxycytidine by halogenated quinoid carcinogens and hydrogen peroxide via a metal-independent mechanism,Free Radic Biol Med, 2013,60: 177-182

10.  Qin H,Huang C H, Mao L, Xia H Y, Kalyanaraman B, Shao J, Shan G Q, Zhu B Z*, Molecular mechanism of metal-independent decomposition of lipid hydroperoxide 13-HPODE by halogenated quinoid carcinogens,Free Radic Biol Med, 2013,63: 459-466

11.  Mao L, Liu Y X,Huang C H, Gao H Y, Kalyanaraman B, Zhu B Z*, Intrinsic Chemiluminescence Generation during Advanced Oxidation of Persistent Halogenated Aromatic Carcinogens,Environ Sci Technol, 2015,49(13): 7940-7947

12.  Shao B, Mao L, Qu N, Wang Y F, Gao H Y, Li F, Qin L, Shao J,Huang C H, Xu D, Xie L N, Shen C, Zhou X, Zhu B Z*, Mechanism of synergistic DNA damage induced by the hydroquinone metabolite of brominated phenolic environmental pollutants and Cu(II): Formation of DNA-Cu complex and site-specific production of hydroxyl radicals,Free Radic Biol Med, 2017,104: 54-63

13.  Gao H Y, Mao L, Li F, Xie L N,Huang C H, Shao J, Shao B, Kalyanaraman B, Zhu B Z*, Mechanism of Intrinsic Chemiluminescence Production from the Degradation of Persistent Chlorinated Phenols by the Fenton System: A Structure-Activity Relationship Study and the Critical Role of Quinoid and Semiquinone Radical Intermediates,Environ Sci Technol, 2017,51(5): 2934-2943

14.  Gao H Y, Mao L, Shao B,Huang C H, Zhu B Z*, Why Does 2,3,5,6-Tetrachlorophenol Generate the Strongest Intrinsic Chemiluminescence among All Nineteen Chlorophenolic Persistent Organic Pollutants during Environmentally-friendly Advanced Oxidation Process?,Sci Rep, 2016,6:

15.  Shan G Q, Yu A, Zhao C F,Huang C H, Zhu L Y, Zhu B Z*, A Combined Experimental and Computational Investigation on the Unusual Molecular Mechanism of the Lossen Rearrangement Reaction Activated by Carcinogenic Halogenated Quinones,J Org Chem, 2015,80(1): 180-189

16.  Li L X Y, Hu L G, Zhou Q F,Huang C H, Wang Y W*, Sun C, Jiang G B, Sulfidation as a Natural Antidote to Metallic Nanoparticles Is Overestimated: CuO Sulfidation Yields CuS Nanoparticles with Increased Toxicity in Medaka (Oryzias latipes) Embryos,Environ Sci Technol, 2015,49(4): 2486-2495

17.  Zhu B Z*, Shao B, Li F, Liu Y X,Huang C H, An Unusual Double Lossen Rearrangement Reaction: The Novel Molecular Detoxication Mechanism for Hydroxamic Acids,Acta Chim Sin, 2015,73(8): 765-769