环境化学与生态毒理学国家重点实验室

杨仁君

发布时间:2024-06-05  |  【打印】 【关闭

姓名:杨仁君性别:男职称:助理研究员电话:010-62849096E-mail:rjyang@rcees.ac.cn组别:干细胞毒理学研究组研究方向:干细胞毒理学招生专业:环境毒理学、发育生物学

简历:

教育经历 

1. 2008-09至2012-07,安徽师范大学,生命科学学院,生物科学类,学士。

 2. 2012-09至2015-07,中国农业大学,生物学院,微生物,硕士。 

3. 2017-09至2020-07,中国科学院生态环境研究中心,环境化学与生态毒理学国家重点实验室,环境科学,博士。 

工作经历

1. 2015-09至2017-07,中国科学院生态环境研究中心,环境化学与生态毒理学国家重点实验室,科研助理。 

2. 2020-07至2022-05,中国科学院生态环境研究中心,环境化学与生态毒理学国家重点实验室,博士后(特别研究助理)。 

3. 2022-05至今,中国科学院生态环境研究中心,环境化学与生态毒理学国家重点实验室,助理研究员。

社会任职:

 

承担科研项目:

1. 国家自然科学基金委员会,青年科学基金项目,22106174,基于胚胎干细胞模型和转录组分析的全氟类化合物神经发育毒性研究,2022.01-2024.12,24万元,在研,主持。 

2. 国家自然科学基金委员会,重大项目,22193052,生命过程中外源污染物的暴露途径和归趋研究,2022.01-2026.12,431万元,在研,参与。

获奖及荣誉:

 

代表论著:

1.       Renjun Yang, Yuanping Lu, Nuoya Yin, and Francesco Faiola*. Transcriptomic Integration Analyses Uncover Common Bisphenol A Effects Across Species and Tissues Primarily Mediated by Disruption of JUN/FOS, EGFR, ER, PPARG, and P53 Pathways. Environmental Science & Technology.  2023, 57, 1915619168.

2.       Xiaofeng Huang#, Renjun Yang#,  Zijuan Qi,Xudong Wang,Nuoya Yin,Francesco Faiola,Sijin Liu,Ming Gao*. Downregulation of m6A demethylase ALKBH5 promotes AuNP-induced neural stem cell quiescence via regulating ID4 expression. Environmental Science-Nano. 2023, 10:843-854.

3.       Shuxian Zhang, Miaomiao Zhao, Shichang Li, Renjun Yang*, Nuoya Yin, Francesco Faiola*. Developmental toxicity assessment of neonicotinoids and organophosphate esters with a human embryonic stem cell- and metabolism-based fast-screening model. Journal of Environmental Sciences (China), 2023, 137:370-381.

4.       Renjun Yang, Shuyu Liu, Nuoya Yin, Yang Zhang, Francesco Faiola*. Tox21-Based Comparative Analyses for the Identification of Potential Toxic Effects of Environmental Pollutants. Environmental Science & Technology, 2022, 56(20):14668-14679.

5.       Renjun Yang, Nuoya Yin, Ying Zhao, Dandan Li, Xuanling Zhang, Xingang Li, Yang Zhang*, Francesco Faiola. Adverse events during pregnancy associated with entecavir and adefovir: new insights from a real-world analysis of cases reported to FDA adverse event reporting system. Frontiers in Pharmacology, 2022, 56(20):14668-14679.

6.       Renjun Yang, Shuyu Liu, Xiaoxing Liang, Nuoya Yin, Linshu Jiang, Yang Zhang*, Francesco Faiola*, TBBPA, TBBPS, and TCBPA disrupt hESC hepatic differentiation and promote the proliferation of differentiated cells partly via up-regulation of the FGF10 signaling pathway. Journal of Hazardous Materials, 2021, 401: 123341.

7.       Renjun Yang, Shuyu Liu, Xiaoxing Liang, Nuoya Yin, Ting Ruan, Linshu Jiang, Francesco Faiola*. F-53B and PFOS treatments skew human embryonic stem cell in vitro cardiac differentiation towards epicardial cells by partly disrupting the WNT signaling pathway. Environmental Pollution, 2020, 261: 114153.

8.       Nuoya Yin#, Renjun Yang#, Shaojun Liang, Shengxian Liang, Bowen Hu, Ting Ruan, Francesco Faiola*. Evaluation of the early developmental neural toxicity of F-53B, as compared to PFOS, with an in vitro mouse stem cell differentiation model. Chemosphere, 2018, 204: 109-118.

9.       Renjun Yang, Xingchao Liu, Ying Wen, Yuan Song, Zhi Chen*, Jilun Li. The PhoP transcription factor negatively regulates avermectin biosynthesis in Streptomyces avermitilis. Applied Genetics and Molecular Biotechnology, 2015, 99: 10547-10557.

10.     杨仁君, 任悦, 沈素, 殷诺雅, Francesco Faiola, 张杨*. 人多能干细胞在环境污染物风险评估中的应用与展望. 生态毒理学报, 2020, 15(3): 47-55. 

11.     杨仁君, 梁小星, 郭恒, 王维娜, 沈素, 殷诺雅, Francesco Faiola, 张杨*. 人胚胎干细胞在药物毒性风险评估中的研究进展. 现代药物与临床, 2019, 34(11): 3491-3496.


 

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