殷诺雅

发布时间:2018-07-09  |  【打印】 【关闭

  
姓名:殷诺雅 性别:女职称:副研究员电话:010-62849096E-mail:nyyin@rcees.ac.cn组别:干细胞毒理学研究组研究方向:干细胞毒理学招生专业:环境毒理学、发育生物学
  

    简历:

  教育经历

  2009/07-2015/01,中国科学院生态环境研究中心 环境化学与生态毒理学国家重点实验室 环境科学,博士 导师:江桂斌院士

  2005/09-2009/06,北京大学医学部 药学院,学士

  工作经历

  2019/03-至今,中国科学院生态环境研究中心, 环境化学与生态毒理学国家重点实验室,副研究员

  2015/05-2019/02,中国科学院生态环境研究中心,环境化学与生态毒理学国家重点实验室,助理研究员

  

  承担科研项目:

  1.国家自然科学基金面上项目,21876197,基于人胚胎干细胞胰腺分化模型研究全氟类化合物与糖尿病发病的相关性,2019/01-2022/12,65万元,在研,参与

  2.国家自然科学基金青年基金,21707160,基于胚胎干细胞研究双酚A及替代物在神经发育过程中对轴突导向的影响,2018/01-2020/12,24万元,在研,主持

  3.国家自然科学基金面上项目,21577166,利用多能干细胞研究环境污染物的健康效应及风险评估,2016/01-2019/12,87.68万元,在研,参与

  4.中国科学院战略性先导科技专项(B类),XDB14040301,典型污染物对干细胞分化和癌变的影响机制,2014/07-2019/7,1482.1万元,在研,参与

  

  代表论著:

1.      Nuoya Yin, Xiaoxing Liang, Shengxian Liang, Shaojun Liang, Renjun Yang, Bowen Hu, Zhanwen Cheng, Shuyu Liu, Hengzhi Dong, Sijin Liu, Francesco Faiola*. Embryonic stem cell- and transcriptomics- based in vitro analyses reveal that bisphenols A, F and S have similar and very complex potential developmental toxicities. Ecotoxicology Environmental Safety. 2019, 176, 330-338.

2.      Yang Zhang#, Nuoya Yin#, Shengxian Liang, Su Shen, Dandan Li, Francesco Faiola*. 5-fluorouracil-induced neurotoxicity in rat cerebellum granule cells involves oxidative stress and activation of caspase-3 pathway. International Journal of Clinical and Experimental Medicine. 2019, 12(3), 2334-2343.

3.      Nuoya Yin#, Bowen Hu#, Renjun Yang, Shaojun Liang, Shengxian Liang, Francesco Faiola*. Assessment of the developmental neurotoxicity of silver nanoparticles and silver ions with mouse embryonic stem cells in vitro. Journal of Interdisciplinary Nanomedicine. 2018, 3(3), 133-145.

4.      Nuoya Yin#, Renjun Yang#, Shaojun Liang, Shengxian Liang, Bowen Hu, Ting Ruan, Francesco Faiola*. Evaluation of the early developmental neural toxicity of F-53B, as compared to PFOS, with an in vitro mouse stem cell differentiation model. Chemosphere. 2018, 204, 109-118.

5.      Nuoya Yin#, Shaojun Liang#, Shengxian Liang, Renjun Yang, Bowen Hu, Zhanfen Qin, Aifeng Liu, Francesco Faiola*. TBBPA and Its Alternatives Disturb the Early Stages of Neural Development by Interfering with the NOTCH and WNT Pathways. Environmental Science & Technology. 2018, 52 (9), 5459-5468.

6.      Nuoya Yin#, Shengxian Liang#, Shaojun Liang, Bowen Hu, Renjun Yang, Qunfang Zhou, Guibin Jiang, Francesco Faiola*. DEP and DBP induce cytotoxicity in mouse embryonic stem cells and abnormally enhance neural ectoderm development. Environmental Pollution. 2018, 236, 21-32.

7.      Francesco Faiola#,*, Nuoya Yin#, Miguel Fidalgo, Xin Huang, Arven Saunders, Junjun Ding, Diana Guallar, Baoyen Dang, and Jianlong Wang*. NAC1 Regulates Somatic Cell Reprogramming by Controlling Zeb1 and E-cadherin Expression. Stem Cell Reports. 2017, 9 (3), 913-926.

8.      Nuoya Yin, Xinglei Yao, Zhanfen Qin, Yuan-Liang Wang, Francesco Faiola*. Assessment of Bisphenol A (BPA) neurotoxicity in vitro with mouse embryonic stem cells. Journal of Environmental Sciences. 2015, 36, 181-187.

9.      Francesco Faiola*, Nuoya Yin, Xinglei Yao, Guibin Jiang. The Rise of Stem Cell Toxicology. Environmental Science & Technology. 2015, 49 (10), 5847-5848.

10.    Nuoya Yin, Xinglei Yao, Qunfang Zhou, Francesco Faiola*, GuibinJiang. Vitamin E attenuates silver nanoparticle-induced effects on body weight and neurotoxicity in rats. Biochemical and Biophysical Research Communications. 2015, 458 (2), 405-410.

11.    Nuoya Yin, Yang Zhang, Zhaojun Yun, Qian Liu, Guangbo Qu, Qunfang Zhou, Ligang Hu, Guibin Jiang*. Silver nanoparticle exposure induces rat motor dysfunction through decrease in expression of calcium channel protein in cerebellum. Toxicology Letters. 2015, 237 (2),112-120.

Nuoya Yin , Qian Liu , Jiyan Liu , Bin He , Lin Cui , Zhuona Li , Zhaojun Yun , Guangbo Qu , Sijin Liu , Qunfang Zhou* and Guibin Jiang*. Silver nanoparticle exposure attenuates the viability of rat cerebellum granule cells through apoptosis coupled to oxidative stress. Small. 2013, 9 (9-10), 1831-1841.

  

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