简历：

　　教育经历

　　2010/09-2015/06，中国科学院上海药物研究所 药物发现与设计中心 药物设计，博士 导师：蒋华良院士 郑明月研究员

　　2006/09-2010/06，沈阳药科大学 药学院，学士

　　工作经历

　　2015年7月-至今，中国科学院生态环境研究中心，环境化学与生态毒理学国家重点实验室，助理研究员

　　社会任职：

　　1. 中国毒理学会分析毒理专业委员会青年委员

　　承担科研项目：

　　1. 国家自然科学基金青年科学基金项目，典型环境雌激素结构与其引发的功能基因集表达变化相关关系及系统毒理机制，2017.01-2019.12，20万元，在研，主持

　　2. 国家自然科学基金面上项目，大气细颗粒物环境持久性自由基原位生成和稳定性的影响机制理论研究，2018.01-2021.12，65万元，在研，参加

　　3. 国家自然科学基金重大研究计划项目，效应导向的典型共存污染对大气细颗粒物环境持久性自由基毒性影响的化学机制研究，290万，2018.01-2021.12，295万元，在研，参加

　　代表论著：　

1.      Liu Xian; Zhang Huazhou; Pan Wenxiao; Xue Qiao; Fu Jianjie; Liu Guorui; Zheng Minghui; Zhang Aiqian^*，A novel computational solution to the health risk assessment of air pollution via joint toxicity prediction: A case study on selected PAH binary mixtures in particulate matters, Ecotoxicology and Environmental Safety, 2019, 170(15): 427~435

2.      Liu Xian^#; Gao Yuan^#; Peng Jianlong; Xu Yuan; Wang Yulan; Zhou Nannan; Xing Jing; Luo Xiaomin; Jiang Hualiang^*; Zheng Mingyue^*, TarPred: a Web Application for Predicting Therapeutic and Side Effect Targets of Chemical Compounds., Bioinformatics, 2015.6.15, 31(12): 2049~2051

3.      Liu Xian; Xu Yuan; Li Shanshan; Wang Yulan; Peng Jianlong; Luo Cheng; Luo Xiaomin^*; Zheng Mingyue^*; Chen Kaixian; Jiang Hualiang, In Silico Target Fishing: Addressing a "Big Data" Problem by Ligand-based Similarity Rankings with Data Fusion, Journal of Cheminformatics, 2014, 6(33): 33-1~33-14

4.      Zheng Mingyue^#; Liu Xian^#; Xu Yuan; Li Honglin; Luo Cheng; Jiang Hualiang^*, Computational Methods for Drug Design and Discovery: Focus on China, Trends in Pharmacological Sciences, 2013.10, 34(10): 549~559

5.      Liu Xian; Shen Qiancheng; Li Jing; Li Shanshan; Luo Cheng; Zhu Weiliang; Luo Xiaomin^*; Zheng Mingyue^*; Jiang Hualiang, In Silico Prediction of Cytochrome P450-mediated Site of Metabolism (SOM), Protein and Peptide Letters, 2013.3, 20(3): 279~289

6.      Yang Xuezhi; Liu Xian; Zhang Aiqian; Lu Dawei; Li Gang; Zhang Qinghua; Liu Qian^*; Jiang Guibin^*, Distinguishing the Sources of Silica Nanoparticles by Dual Isotopic Fingerprinting and Machine Learning, Nature Communications, 2019, 10: 1620

7.      Li Jing; Liu Xian; Li Shanshan; Wang Yulan; Zhou Nannan; Luo Cheng; Luo Xiaomin; Zheng Mingyue^*; Jiang Hualiang; Chen Kaixian, Identification of Novel Small Molecules as Inhibitors of Hepatitis C Virus by Structure-Based Virtual Screening, International Journal of Molecular Sciences, 2013.11, 14(11): 22845~22856

8.      Xu Yuan; Liu Xian; Li Shanshan; Zhou Nannan; Gong Likun; Luo Cheng; Luo Xiaomin^*; Zheng Mingyue^*; Jiang Hualiang; Chen Kaixian, Combinatorial Pharmacophore Modeling of Organic Cation Transporter 2 (OCT2) Inhibitors: Insights into Multiple Inhibitory Mechanisms, Molecular Pharmaceutics, 2013.12, 10(12): 4611~4619

9.      Xu Yuan; Liu Xian; Wang Yulan; Zhou Nannan; Peng Jianlong; Gong Likun^*; Ren Jing; Luo Cheng; Luo Xiaomin^*; Jiang Hualiang; Chen Kaixian; Zheng Mingyue^*, Combinatorial Pharmacophore Modeling of Multidrug and Toxin Extrusion Transporter 1 Inhibitors: a Theoretical Perspective for Understanding Multiple Inhibitory Mechanisms , Scientific Reports, 2015.9.2, 5(13684): 1~13

10.    Pan wenxiao; Chang jiamin; Liu Xian; Xue Qiao; Fu Jianjie; Zhang aiqian Interfacial formation of environmentally persistent free radicals—A theoretical investigation on pentachlorophenol activation on montmorillonite in PM2.5, Ecotoxicology and Environmental Safety, 2019, 169: 623~630